Varanasi: A scientist from the Center for Genetic Disorders, the Science Institute, Banaras Hindu University, Dr.
Chandana is the only scientist from India in the Global Research Team, who has found a gene responsible for human fingerprint patterns.
Landmark studies have recently been published in one of the most prestigious scientific journals of science cells, has found that fingerprint patterns in humans are determined by the gene of limb development.
This study was conducted by an international scientist consisting of Shanghai, Australia, England, USA and India.
Dr.
Chandana said that fingerprints are known to be unique to an individual but they can generally be categorized into three types of-traces, loops, and whorl.
To understand the gene responsible for the fingerprint pattern, the team studied DNA from more than 23,000 individuals from various ethnic groups and identified 43 genetic locuses that contributed to fingerprint patterns.
Interestingly, they found that most of these genetic locuses came from genes involved in the path of development of limbs than genes related to skin development.
One of the top genes identified is EVI1, which has been known for its role in the development of embryonic legs.
When the team was further tested using the EVI1 mouse model, they found that mice are genetically modified with a decrease in EVI1 expression developing abnormal skin patterns in their digits compared to normal type wild mice.
Furthermore, this study also revealed the correlation of fingerprint patterns with hand proportions.
For example, people with circle-shaped fingerprints on both small fingers they tend to have small fingers longer than others.
“This is one of the most comprehensive studies about genetics of fingerprint and study patterns like this helping us better understand the human phenotype or how we vary from each other,” said Dr.
Chandana, added, “There is no fingerprint in mice, But it is interesting to develop a sliding print method (fingerprint analog).
When we compare the pattern of this ridge between modified EVI1 and normal mouse, we find similar results such as humans.
“This is one of the most comprehensive studies carried out on the genetics of fingerprint patterns .
The coordinator of the Genetic Disorder Center Prof.
Parimal Das said that such comprehensive research involved the genetics of the population, mouse models, cell biology, protein tissue was a strong approach to revealing the biology of complex traits and the requirement of hours.
“The genetic fingerprint association with the development of limbs is a new dimension of biology developments that might have important social implications.
The participation of Dr.
Chandana in this study reflects its enthusiasm for an investigation in the mystery of nature,” said Director of the Institute of Science Prof.
Anil Kumar Tripathi.
Deputy Chancellor Bhu Prof.
Sudhir K Jain, “I am happy that our young man Dr Chandana from the center of genetic disorders has published several high-quality research works in cells, one of the most famous science journals.
This research can be a starting point for the use of dermatoglyphics and Genetics is related to identifying default disorders and in public health.
Bhu is at the forefront of human genetic research and I sincerely hope that in the coming years we will have more contributions from Bhu researchers.
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