VARANATION: The team of scientists at the University of Hindu Banaras conducts important studies that will benefit those who suffer chronic injuries, especially with diabetic foot ulcers.
The team led by Prof.
Gopal Nath from the Department of Microbiology, Medical Institute, learned that injuries that take months for years to heal can be cured in a few days or months.
The research findings have been published in the National Biotechnology Information Center, National Institutes of Health, United States.
Other members of the team involved in clinical studies including Prof.
Bhartiya, Prof.
VK Shukla, Dr.
Pooja Gupta, Dr.
Hariskark Singh, Dr.
Dev Raj Patel, Rajesh Kumar, Dr.
Rina Prasad, Subhas Lalkarn.
Even though there are injuries defined as violations on the skin or body tissue due to injury.
Acute wounds are defined as recent breaks that have not developed through the stage of healing.
The wound where the normal healing process stopped because of the underlying pathology (vascular and diabetes etc.) or infections outside the three months are defined as chronic wounds.
While chronic wounds are always infected, contaminated wounds are susceptible to infection.
Infection with antibiotic resistant bacteria and biofilm formations stop healing progress.
These injuries cause significant psychological and physical morbidity.
Traditional care strategies often succeed in healing wounds, he added that there were still many wounds to be observed to them, which leads to respiratory perseverance and infection.
Search for alternatives for antibiotics have now become coercion.
Fortunately, bacteriophage therapy is a solution that reappears for antibiotic antibiotic bacteria.
The Prof Nath team carried out FAG therapy in acute and chronic infected in animal and clinical studies.
This shows efficacy of pseudomonas aeruginosa in the mouse wound model.
Furthermore, they evaluate the efficacy of the phase cocktail in acute and chronic osteomyelitis of animal models caused by staphylococcus aureus resistant metism.
In addition, they also observed the biofilm eradication of wire K in a rabbit wound infection model.
The clinical test of FAG therapy initiated by BHU has reported the topical phase efficacy in the healing chronic wounds in three prospective studies of exploration and no side effects that mimic the results on Vivo animal models.
A clinical study by Gupta shows the important role of bacteriophage therapy in chronic wounds associated with antibiotic bacteria.
This study uses a total of twenty patients with chronic non-healing ulcers for more than six weeks of duration.
A significant increase can be achieved in the form of a complete wound epithelium in a few weeks.
Other studies by Dr Patel who employ forty-eight patients have at least one full thickness wound that meets the requirements that do not recover in six weeks with wound management convention showing promising results, and a significant increase observed in wound healing.
This study projects that specific phase therapy is equally effective regardless of diabetic or non-diabetes patients.
However, healing was relatively delayed in diabetes patients.
He said that both studies provide almost firmly that topical Fag therapy was associated with complete clinical injury healing.
The resistance status of bacterial antibiotics involved in chronic diseases will not affect the results of therapy.
Another successful study by Bhartiya has shown encouraging results in the healing process of acute traumatic wounds that are infected.
The average number of days needed for complete granulation of wounds and achieving half sterility and healing compared to conventional therapy.
Because of the high properties for hosting their bacteria, phase cocktail formulations usually guarantee a broader spectrum of activities and reduce the possibility of the emergence of fag-resistant bacterial mutants.
Therefore, all of these studies use bacteriophage cocktails for therapy.
Bhu’s study found a quick medicine for chronic wounds
