Coronavirus which causes Covid-19, SARS-COV-2, can spread within a few days of the airways to the heart, the brain and almost every organ system in the body, where it can last for months, a study was found.
In what they described as the most comprehensive analysis to the date of distribution of viruses and persistence in the body and brain, scientists at the US National Health Institute said they found pathogens were able to replicate in respiratory cells far outside the respiratory tract.
As a result, it was released online on Saturday in a text that was being reviewed for the publication in the journal Nature, navigate to delay viral licenses as potential contributors to continuous symptoms called old covid sufferers.
Understanding the mechanism in which the virus continues, along with the body’s response to the viral reservoir, promises to help improve care for those who suffer, said the author.
“This is a very important job,” said Ziyad Al-Aly, director of the clinical epidemiology center on the Veteran St.
Louis a health care system in Missouri, who has led a separate study into the long-term effects of Covid-19.
“For a long time now, we have scratched our heads and asked why Long Covid seems to affect so many organ systems.
This paper spends light, and can help explain why long covids can occur even in people who have mild acute disease or asymptomatic.
“Findings have not been reviewed by independent scientists, and most are based on data collected from fatal covid cases, not patients with long covid or” post-acute symptoms of SARS-COV-2, “as well-called.
Controversial findings, the tendency of Coronavirus to infect cells outside the air duct and contested lungs, with many studies that provide evidence for and oppose the possibility.
The research was conducted on Bethesda, Maryland, based on extensive sampling and network analysis taken during the autopsy in 44 patients who died after contracting Coronavirus during the first year of the pandemic in the US, the expense of infection outside the respiratory tract outside the branches outside the channel Breathing and time for viral permits is not well marked, especially in the brain, writing Daniel Chertow, who runs the pathogen section that appears, and his colleagues.
The group detects RNA SARS-COV-2 persistent in various parts of the body, including areas throughout the brain, for 230 days after symptom onset.
This can represent infections with damaged viruses, which have been described in persistent infections with measles viruses, they said.
Unlike other Covid autopsy research, the collection of post-mortem networks is more comprehensive and usually occurs in the time of patient death.
Coronavirusthe Budiding Researchers also use various network preservation techniques to detect and measure viral levels, and grow viruses collected from several tissues, including the lungs, heart, small intestine and the adrenal glands of covid patients who have died during their first week.
.
“Our results collectively show that while the highest load of SARS-COV-2 is in the air and lungs, the virus can spread earlier during infection and infect cells throughout the body, including widely throughout the brain,” Para said Writer.
The researchers argue that pulmonary system infections can produce the initial phase of “viremic”, where viruses are present in the bloodstream and are seeded throughout the body, including crossing the blood-brain barriers, even in patients who experience mild or not symptoms.
One patient in an autopsy study is a teenager who is likely to die due to unrelated seizure complications, showing infected children without severe Covid-19 can also experience systemic infections, they said.
The lack of efficient immune response in tissue outside the pulmonary system may be related to a weak immune response outside the respiratory tract, the author said.
RNA SARS-COV-2 was detected in the brain of all six autopsy patients who died more than a month after developing symptoms, and in most locations were evaluated in the brain in five, including one patient who died 230 days after symptom onset.
Focusing on several areas of the brain is very helpful, Al-Aly said on the St.
Health Care System.
Louis.
“This can help us understand the decrease in neurocognitive or ‘brain fog’ and other neuropsiciatric manifestations of long covid,” he said.
“We must begin to think of SARS-COV-2 as a systemic virus that might be clear in some people, but in other people can last for weeks or months and produce long covid – multifaceted systemic disorders.”