Chandigarh: Permanent intensive care unit (ICU) reduction between Covid-19 patients in the treatment of dexamethasone recorded in a quasi-experimental study by the research team from Sri Teacher RAM Dass Institute of Medical Sciences and Research, Amritsar.
The study aims to evaluate the role of dexamethasone, corticosteroids used for various conditions for their anti-inflammatory and immunosuppressants, in overall death, oxygen support based on high flow nose flow (HFNO) / non-invasive ventilation (NIV), invasive mechanical ventilation needs during Inpatient in Covid-19 patients who are critically ill.
A total of 97 97 sequentially recognized positive patients in the Intensive Care Unit (ICU) of the Tertiary Care Hospital were evaluated to be included, where 79 was included in this study.
Of the total, 40 patients received a dose and placed in group B while the remaining 39 received standard care and was included in group A.
Patients in dexamethasone are constantly monitored for each risk of reactivation of latent infections.
All participants are monitored for narrow control of breathing frequency and oxygen saturation.
The cumulative survival rate of patients in dexamethasone was 97.5% compared to 87.2% of participants in group A, which was given standard care.
Among participants who need low flow oxygen, the cumulative survival event is 100% for both groups.
However, the recovery time and their debit was lower in group B.
Among patients who needed high flow, the NIV survival rate was 71.8% in Group B and 21.4% in group A.
Data analysis carried out by the researchers on The seventh day of treatment shows that of the 20 group B participants in high flow from the day of receipt, 11 was shifted to low flow oxygen.
Conversely, four patients showed a reduction in oxygen requirements and shifted to a low flow of high flow oxygen.
In the next assessment was carried out after two weeks, no patient on the treatment of dexamethasone needed high flow, NIV or mechanical ventilation in group B while 5.2% of group participants needed high flow / NIV.
The average age of the participants in the two groups was 51 years in the Dexamethasone group, 21 hypertension participants compared to 15 in group A.
A total of 27 participants in group B were diabetes and four had a chronic arterial disease while 23 patients on maintenance standards suffer from temporary diabetes have chronic artery disease.
Research findings ‘Dexamethasone Roles in Oxygen Requirements, Death, and Survival Incidents among Covid-19 patients: Experimental Study Quasi’ by Dr.
Lakshmi Mahajan, Dr.
Arvinder Pal Singh Dr.
Akshita Singla and Dr.
Gifty Singh has been published in an anesthetic essay.
and research.
This study concluded that findings can be used to strengthen the design of the treatment protocol for covid patients.