Beijing: Initial Covid-19 cases traced to the market in Wuhan, China, reflected the initial deployment of SARS 17 years before, scientists said in a paper that concluded that animal transmission was the most likely possible pandemic explanation.
The history of the epidemiology of the SARS-COV-2 virus is proportional to the previous Koronavirus outbreak in the previous animal market and offers a simple route for human exposure, Edward Holmes, Andrew Rambutut and 19 other researchers say in review of scientific evidence related to the origin of pandemic.
This paper was released Wednesday ahead of the peer review, and was being prepared for submission to the journal for publication, said one of the authors.
It provides a detailed explanation for the genetic signature of the SARS-COV-2, the initial epidemiology and research conducted in the Wuhan Institute of Virology.
“This is a truly systematic first systematic sift,” Holmes, a professor of Laureate who studied the biology of evolution at the University of Sydney, said in an email.
There is a lot of news coverage from Covid origins in recent months, “Most of the speculation and some of them are only misinformed,” he said.
“We think it’s important to return to core scientific data and clearly and calmly work through what it says to us.” The debate about the appearance of Covid has joined two competing ideas: labelarian laboratories or abundance of animals.
The authors, who also included the Nobel Prize winner Peter Doherty and Director of Wellcome Trust Jeremy Farrar, said there was no evidence that the SARS-COV-2 had the origin of the laboratory, and suspicion came from coincidence that the Pandemic virus was first detected in a city that accommodated the biosafety laboratory The maximum institute that studies Koronavirus and deadly disease, such as Ebola.
Lab accident theory “cannot be fully dismissed,” but it is very unlikely, the author said, compared to “recurrent human contacts that occur regularly in the trade in wildlife.” ‘COCATION COURSE’Failure to investigate and understand the origin of transmission viruses through collaborative research and carefully coordinated “will leave the world that is susceptible to future pandemics arising from the same human activity that has repeatedly placed us on a collision course with a new virus , “They wrote.
Wuhan is the largest city in central China with several animal markets and is the main center for travel and trade, well connected to other areas both in China and internationally saying.
Links to Wuhan, therefore, more likely to reflect the fact that pathogens often need a compacted area to be established.
Based on epidemiological data, Huanan wholesalers of seafood and producing a market in Wuhan is the initial SARS-COV-2 infection center, the researchers said.
Two of the three COVID-19 cases that are the earliest documented directly related to markets sold, wild animals, such as 28% of all cases reported in December 2019.
Overall, 55% of cases during the month have exposure to Huanan or other markets in Wuhan, with these cases are more common in the first half of that month.
Although there are no reservoir bats or hosts of medium animals for SARS-COV-2 have been found so far, transmission of viruses from one animal species to the other is probably not detected, the author said.
The initial SARS-COV case is not possible to spread the virus to others, and only a small portion of the abundance of animals to humans produces a large outbreak.
The pandemic virus evolved in the host environment “very similar, if it is not identical,” for the Coronavirus bat which is considered to match the closest match with SARS-COV-2, researchers at Sun Yat-sen University and Guangzhou University said.
Their research, released July 1 on the Prefrint server, was found it would be difficult to duplicate SARS-COV-2 in cell culture under laboratory conditions.