By passing the day, we see the emergence of a newer virus variant spread throughout the world.
While the variant comes from the same tension, all have different features that make it less or worse than.
Dr.
Mala Kaneria, Consultant, Department of Infectious Disease, Jaslok Hospital, Mumbai helped resolve your doubts.
How many Sarscov2 variants are in India?
Viruses are basically known to mutate and mutations are important to survive and propagate them.
Sarscov2’s original Wuhan strain has mutated several times since its appearance.
Many variants have received the attention of health authorities, such as Alpha, Beta, Gamma, Delta, Delta Plus, Lambda, ETA and Lota.
B.11.318 and B.1.617.3 are several other variants.
What is the difference between a variant?
Delta variant (B.1.617.2), who was first discovered in India, was an interesting variant (VOI) in April 2021 and then became a Varian to a concern (VOC) in May 2021, when it caused the second to turn off the two covid waves -19, which destroys the country.
Delta has emerged as a threat throughout the world because most of the current Covid-19 cases in the world are Delta variants.
The Delta variant is not only a few times more transmitting and causing more severe symptoms but also 8 times less effective against the vaccine compared to the original strain of Covid-19.
This mutant is now found in most countries and is responsible for wave cases in the UK and Israel.
Delta Plus (AY.1) variant, derivative of Delta waves, containing the mutation of the K417N surge protein, which was first seen in the Beta (South Africa) variant.
This is a Varian that is a concern (VOC) since it was observed that the vaccine was not too effective against the relevant beta tension.
Kappa variant (B.1.617.1), also related to the Delta variant, has two mutations (L452R and E484Q), where the L452R is an escape mutation that provides immune protection against viruses.
Two Kappa cases have been reported from Uttar Pradesh recently.
Lambda, seventh VOI, contains mutations of L452Q and F490S, comes from Peru, the state with the highest mortality.
Kappa and Lambda are currently labeled as a variant variant (VOI) by WHO.
Which is more deadly or dangerous?
Delta is the most deadly because it is responsible for a large number of cases and increasing death during the second wave in India.
Delta Plus, becoming a derivative of Delta also has attributes of transmission enhancements, the ability to bind stronger to receptors on pulmonary cells, and the potential to avoid antibody responses, although there is no hard data about death.
However, some scientists believe that the K417N can really weaken Delta Plus tensions and may not be deadly such as delta tensions.
Not much is known about Kappa and Lambda’s death, which is currently not found in India.
Why is Delta Plus called AD VOC while Lambda is called VOI?
If the variant is found to be more transmitting, more resistant to antibodies, or cause a more severe disease, it is set as VOC.
Delta and maybe Delta Plus has shown these traits and therefore called VOC.
However, there were no cases of lambda in India so far and turned out unknown, therefore only VOI today.
Is this new vaccine vaccine hold?
The existing vaccine works against the original Delta variant but is less effective on those who do not install strong immune responses.
Delta Plus variant due to the Runaway Mutation of the K417N, can avoid vaccines and antibodies better than Delta.
But leading vaccines are considered to offer protection against serious illness and hospitalization of most strains.
Which vaccine is more effective?
Astrazeneca and N Pfizer vaccines remain extensively effective against Delta and Kappa variants.
There is no extensive escape evidence indicating that the generation of vaccines today will provide protection against the lineage B.1617.
However, the concentration of neutralization antibodies in the blood can reduce, which can cause some breakthrough infections.
The latest data shows that the third booster dose of PFIZER will be more effective against the delta strain, as an antibody for this variant decreases faster.