New Delhi: Why do some people continue to have symptoms, such as fatigue, poor memory and hair loss, long after recovering from Covid-19? The answer to this can be hidden in their Microbiota gut make-up, a new study published online in the intestinal journal suggest.
In this study, scientists tracked changes in intestinal microbiomas – trillions of bacteria, fungi and other microbes that inhabited the digestive tract – from 106 patients with a variety of covid severity by analyzing their stool samples and compare it with the composition of the microbiome intestine from a group of 68 people who did not have Covid.
They found that among the species of bacteria found in patients with long covid, 28 reduced and 14 enriched both in hospital entrance tickets and three and six months after exiting.
At six months, patients with a long covid have significantly less ‘friendly’ F.
Prausnitzii, and BLAUTIA OBEUM and greater abundance of ‘unfriendly’ ruminococcus gnavus andbacteroides vulgatus than people who do not have covid.
On the other hand, the intestine of the microbioma of those who did not develop long Covid showed only 25 bacterial species changes in hospital entrance tickets, and this recovered fully after six months, this study was led by Professor Siew from the University of China Hong Kong found.
Dr.
S K Sarin, noted gastroenterologists and representatives of Chancellor of Institute of Heart and Bilier, told TII that research findings had the potential to change the management protocol for long covid.
“Our bodies have trillions of microbes, including bacteria, viruses and fungi.
They usually live in symbiosis with the body.
This research shows external inserts such as Covid viruses, which also multiply in the intestinal cells, can cause dysbiosis or imbalance in the microbiota gutter, which leads to an increase in the causes of pathogenic diseases or bacteria and relative reduction in the presence of good bacteria, resulting in long-lasting side effects, “he said.
Dr.
Sarin said based on this theory, one can provide good bacteria in the form of probiotics to correct imbalances.
Dr.
Randhir Sud, Chairperson, Institute of Digestion and Hepatobilier, Medanta – Medicine, said there were nearly 38 trillion bacteria, viruses and fungi in the human intestine which affected the various functions of the human metabolism and immune.
“We now realize that microbial gut composition is not the same at all and plays an important role in our vulnerability to a disease.
For Covid too, this is possible and people with certain intestinal microbial compositions may be susceptible to severe or long covid diseases,” he said.
Dr.
said it was possible to change this composition in the short term with special special antibacterial probiotics and drugs, but whether it would help in the prevention of old Covid unknown.
Dr.
Ishi Khosla, a clinical nutritionist, said people who recovered from Covid must be advised to eat healthy, so that inflammation caused by infection in the intestine can be cured.
“It might be good to add probiotics or other supplements with a special focus to provide fertile soil for good bacterial growth,” Dr.
Khosla said.