Nagpur: In significant development, a systematic safety testing study led by the Indian Veterinary Research Institute (IVRI) with the history of the History of Society (BNHS) and the Royal Society of Bird Protection (RSPB) has identified Tolfenamic acid as the second anti-inflammatory drugs non -teroid non-steroid confirmed (NSAID) after Meloxicam.
In 2003, the use of Diklofenac animals to treat livestock as painkillers was found as a cause of disaster worms in South Asia.
Meloxicam was tested in 2006 and found either safe for nasar and effective birds in treating livestock.
However, now Tolfenamic acid has been identified as a Second Confirmed NSAID-Heral-Bird.
It has been found after 38 nasar birds and each of them from a white-backed herry and a long-headed herry is given a dose of Tofenamic.
Speaking with Toi, Chris Bowden, a globally threatened species officer & saved the Asian Nasar from the extinction manager (Save), said, “Since the 2006 National Prohibition of Veterinary Medicine, until now we can only recommend a safe alternative medicine for use in livestock .
Having tolfenamic acid as a second safe alternative is a big boost and we hope this helps veterinarians and farmers to avoid deadly alternative use, including aceclofenac, nimesulide and ketoprofen.
“Bowden, who also operate with the IUCN owl specialist group,” This is a pleasant change to have good news for once.
More than 97% of all Nasar birds have been lost, so unless the news like this can make a real difference for decision makers, Indian Nasar birds can be cursed on history books.
“Bowden said 38 Himalayan Nasar birds caught wild, together Ngan Nasar’s white prisoners and long bills from the population of conservation breeding, given a dose of tolfenamic acid with oral gavage at the maximum level that might be encountered by bird giving.
on the carcass in the wild.
This is calculated based on the dichlofenax concentration found in livestock carcasses in India, which shows that veterinarians and livestock owners regularly provide a dose of this drug much higher than the recommended level.
In addition, four Himalayan Griffon also fed buffalo meat from animals and was given the recommended dose of Tolfenamic acid before death.
Although two Griffon Himalayas remembered a very high dose by Gavage died, all other birds survived without increased uric acid levels in the blood, which was a sign of kidney failure caused by NSAID poisoning.
These findings indicate that Tolfenamic acid is safe for wild nasar birds at the level of drugs that tend to be exposition.
Dr.
Chandra Mohan, Ivri scientist and the main researcher, said, “Any available painkiller drugs have a slightly different properties, and veterinarians often complain do not have the second choice of NSAIDs.
But Tolfenamic acid has been found as a second secure NSAID medicine.” DR Vibhu Prakash, the main scientist Director of the Bombay Program Natural History (BNHS), “by testing the first at the Himalayas Griffon who is less threatened, we can build a comparative security of drugs.
We then test it in the most threatened species held at the breeding center on Pinjore, Haryana.
The results of this study were reported in the IVRI report.
“Tolfenamic acid has been licensed and produced by a number of different Indian producers, out of patents, and at the same price as other drugs.
Professor Rhys Green of Cambridge University UK, and the Chair of the Save Consortium, said: “After 16 years and a considerable effort in NSAID safety testing in nasar birds we have found a safe NSAID a herry bird to use in cattle.
It’s important and welcome news .
This will reduce the pressure to use toxic alternatives such as aceclofenac, ketoprofen, flunixin and nimesulide, which is still available and legally used in the region.
“Findings * Tolfenamic acid is identified as a second-safe hering drug * Efforts to produce results after 16 years * Dosage given to 38 nasar birds * will reduce pressure on toxic alternatives * produced by many Indian companies