Bengaluru: From how kidney stones are formed in fruit flies to study the marker of the gene, from the Heat Sink function in the micro to crystallization, an expert committee established by the Indian Space Research Organization (ISRO) has chosen five of the 28 proposals received from various institutions for Sending as a charge to conduct experiments in space, as part of the notched mission that has signed the MoU with the Institutes for five loads being built.
“How many of these five will go on the first mission that is not printed and how many will depend on their maturity and readiness.
We have signed a memoranda understanding (MoU) with the Institute which builds five selected charges by the Expert Committee.
Apart from this, we will send the content of radiation measurement and half humanoid – vyomitra – as part of an unprinted mission, “said Nair to Tii.isro Chairman K Sivan said the space agent wants to fly Vyomitra in the mission without the first crew in the mission so to get the knowledge of the environment and Other aspects.
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from five selected trials, two will be biologically, and we have three non-biological charges.
Our Institute has signed a mous with: Indian Institute of Space Science and Technology (IIST), University of Agricultural Sciences (UAS) Dharwad, Tata Institute of Fundamental Research (TIFR), IIT-Patna, CSIR Indian Institute of Chemical Technology (CSIR-IICT) and Jawaharlal Nehru Center for Advance Scientific Research (JNCASR), “added Sivan.
From biological experiments, IIST and Joint UAS will send a charge to learn “the formation of kidney stones in Drosophila Melanogaster (fruit flies)”, while TIFR will use the same charge “to study the SIRT1 mark marker effect on fruit flies” .as per paper published Globally, simple but elegant Drosophila Melanogaster appears as a strong translation model of human diseases, including nephrolithiasis and can provide important information that is important for our understanding of stone formation.
TIFR studies are also important because sIrt1 genes encode sirtuin 1, “Protein members from the Non-Sir2 information regulator (SIR2) Protein F Amily, which has received great attention as an epigenetic regulator for a good area in human physiology”.
The researchers have so far found that changes in sirtuin expression are very important in some diseases, including metabolic syndrome, cardiovascular disease, cancer and neurodengeration.
“Three other experiments are: studies of crystallization phenomenon in CSIR-IICT; Heat sinks to handle very high heat flux in micro by IIT-Patna and the characteristics of mixing fluid studies in micro by JNCASR,” added Sivan.