Categories: Nagpur

With ‘Omicron’s Stealth’ Skip SGTF RT-PCR, Test Shifts to Omisure Kit

Nagpur: In the midst of increasing the appearance of the new Omicron sub-lineage BA.1, BA.2 and BA.3 in more symptomatic patients, the laboratory in the city will soon switch to the RT-PCR kit that was accidentally developed for their early detection.
While Drop Gen – Indication of omicron variant B1.1.529 and the lineage is present – reported in the kit ‘Gene Target Failure (SGTF), sub-lineage passes in RT-PCR Run.
Recently, the SGTF test at 71 samples became positive for 70 in IGGMCH where similar tests on 93 other samples at GMCH expressed 89 positive.
The positive test shows the existence of genes ”, so aside the omicron variant, while the possibility of the sub-variant requires a whole genome sequencing.
Gen ‘s’ detection in most samples that experienced the SGTF RT-PCR kit had left the authority in GMCH and IGGMCH confused.
Officials said that the RT-PCR kit was persecuted appropriately to identify Omicron and its sub-lineage BA.1 BA.2 and BA.3, which is also called ‘silealh omicron’.
Early detection will help the doctor in deciding treatment protocols for symptomatic patients, especially with a decrease in oxygen levels.
The doctor is in a dilemma on care for patients who need O2 support, in NIV or BIPAP.
On Tuesday, the state assignment unit also instructed medical colleges and supervision officials to choose the Omisure kit instead of the SGTF kit.
Interestingly, the laboratory at IGGMCH, GMCH and AIIMS-Nagpur have bought 1,000 SGTF kits each of these months.
Dr.
Meena Mishra, the head of professor and head, the Department of Microbiology, AIIMS, said the focus of detecting omicron or delta variants is now in patients who need hospital admission.
“We need to check the variant that is in the sample of medium covid patients to severe.
Omisur will help conclude if the patient is positive for omicrons and the lineage or not The situation in which a patient is positive for Omicron or not, “he said.
Dr.
Mishra added that the omisure test will come as a big financial assistance for patients who might not need cocktail therapy.
Dr.
Krishna Khairnar, Head of the Environmental Virology cell, Neer, said the four series of genome sequencing carried out until now by their lab had raised the omicron status and its lineage in the given population.
“Stopping the SGTF run for omicron supervision is a good step because they are mostly Miss BA.2.
As we reported in the last sequencing series, BA.2 consists of 66% positive samples of SARS-COV-2 of symptomatic cases,” He said.
On January 24, TOI has reported about the fourth neeri genome sequencing series where he found the dominant BA.2 variant among symptomatic patients.
The variant was also found in one of six patients treated in a private hospital.
To capture the virus quickly – State Supervision Officer said Omicron was in the community transmission stage – hence, focus must be in patients who reached the hospital – quick information about variants that affect them will help doctors – SGTF kits do not help harvest omicron – so far, so far, so far, It is believed that a sample that did not show the drop of the Gen’s’ Delta variant – study by neeri and CSIR-NCL showed BA.2 to be dominant – ba.2 not visible in SGTF – Omisur can detect all three omicron sublineages BA.1, BA.2 and BA.3

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